Are People Overoptimistic about the Effects of Heavy Drinking? [J Risk Uncertain. 2013] – PubMed

Heavy drinkers have a sense that excessive alcohol consumption isn’t doing them much good. But, paradoxically, they believe the rapid and complex visuomotor integration required for driving is unaffected. Presumably the lack of conscious access to the non-declarative habit systems of the brain (tell me exactly how to drive a car, play a musical instrument… Read More

The Art and Science of Recognising Yourself

Originally posted on Wellcome Trust Blog:
As a new art installation by Mark Boulos, Echo, explores the nature of self-recognition and representation, his collaborator, Cognitive Neuroscientist Professor Olaf Blanke, explains a little more about the subject: how and when we are able to recognise ourselves, our artistic representation and experience of self portraits, and what…

Risk factors for the development of depression in patients with hepatitis C taking interferon-α

Risk factors for the development of depression in patients with hepatitis C taking interferon-α Neuropsychiatr Dis Treat. 2011;7:275-92. doi: 10.2147/NDT.S13917. Epub 2011 May 15. [Download the paper] Smith KJ, Norris S, O’Farrelly C, O’Mara SM. Trinity College Institute of Neuroscience. Interferon-α, currently used for the treatment of hepatitis C, is associated with a substantially elevated risk of depression. However,… Read More

Interactions Between Paired-Pulse Facilitation, Low-Frequency Stimulation And Behavioral Stress In The Pathway From Hippocampal Area CA1 To The Subiculum: Dissociation Of Baseline Synaptic Transmission From Paired-Pulse Facilitation And Depression Of The Same Pathway.

Originally posted on Shane O'Mara:
The summation of these three EPSPs generates an action potential. (Photo credit: Wikipedia) Here’s an old and difficult to access paper (Download: Commins & O’Mara Psychobiol) of ours from Psychobiology – from the days before all journals were online. Hard to remember those days now… Psychobiology evolved into Cognitive, Affective, & Behavioral…

Everyday episodic memory in amnestic mild cognitive impairment: a preliminary investigation.

Everyday episodic memory in amnestic mild cognitive impairment: a preliminary investigation. BMC Neurosci. 2011 Aug 4;12:80. doi: 10.1186/1471-2202-12-80. [Download the paper] Irish M, Lawlor BA, Coen RF, O’Mara SM. Decline in episodic memory is one of the hallmark features of Alzheimer’s disease (AD) and is also a defining feature of amnestic Mild Cognitive Impairment (MCI), which is posited as a… Read More

Want to know more about the unreliable nature of memory? Read this

Originally posted on TED Blog:
Elizabeth Loftus studies false memories. As she describes in her TED Talk, The fiction of memory, she has implanted erroneous memories of childhood trauma into adult study subjects as part of her work. She has pinpointed failures in eyewitness testimonies. She’s found that misinformation can reshape taste preferences. And, she’s…

Elizabeth Loftus on embedding false memories in U.S. soldiers

Originally posted on TED Blog:
Photo: Thinkstock “We can’t reliably distinguish true memories from false memories,” declares psychologist Elizabeth Loftus in today’s talk. She’s spent the past forty years studying the memory, and has reached some mind-blowing conclusions about what we know, and what we think we know. Here, she shares more detail about her…

Evidence for cognitive-enhancing effects of modafinil and methylphenidate is surprisingly thin – perhaps because wakefulness-promotion and cognitive enhancement are confused

There is huge media and other interest in cognitive-enhancing drugs. A few minutes searching on the internet will uncover stories of students and others using modafinil and some other compounds in an effort to enhance their own cognitive function. The evidence for the cognitive-enhancing effects of these compounds is surprisingly thin, however, despite claims about… Read More

The psychostimulant modafinil facilitates water maze performance and augments synaptic potentiation in dentate gyrus.

The psychostimulant modafinil facilitates water maze performance and augments synaptic potentiation in dentate gyrus. [download here] Neuropharmacology. 2010 Jul-Aug;59(1-2):9-19. doi: 10.1016/j.neuropharm.2010.03.010. Epub 2010 Mar 27. Tsanov M, Lyons DG, Barlow S, González Reyes RE, O’Mara SM. Source Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin 2, Ireland. Abstract Modafinil is a psychostimulant drug used widely for the treatment of… Read More