Hippocampal-anterior thalamic pathways for memory: uncovering a network of direct and indirect actions.

Our major theoretical take and review of the extended brain systems that support explicit, declarative memory in the brain. [Download the paper.] Take-home message: there’s a lot more to memory than the hippocampal formation, and you forget (!) the connected thalamic structures at your peril, because the anterior thalamus provides a subcortical circuit supporting memory and spatial… Read More

Aerobic exercise improves hippocampal function and increases BDNF in the serum of young adult males.

Take-home message: It is becoming increasingly accepted that substantial, sustained low-impact aerobic exercise has profound effects on neurocognitive function in the aged (see, for example, this very important paper from Art Kramer’s group). We here focus on a young and sedentary population, using tasks that tap into hippocampal function. We also measure circulating brain-derived neurotrophic factor (BDNF) as a proxy for brain BDNF. We… Read More