Month: October 2014

TCIN 2014 Symposium Schedule: Tuesday November 4, 2014

TCIN 2014 Symposium Schedule Date: Tuesday November 4, 2014 Venue: Lecture Theatre LB 11, Lloyd Building, Trinity College Coffee: 0930-1000. Symposium start: 1000 Our Plenary speakers in 2014: Prof. Kate Jeffrey, UCL: lab Prof. Bruno Poucet: lab Prof Lissette Mendez de la Prida: lab Plus a host of locals: Dr Marian Tsanov, Niamh McGuinness, Dr Jens Hillebrand, Prof Andrew Harkin, Prof Connail McCory,… Read More

Why you need lots of good quality sleep: Sleep loss affects work performance, ethics, memory and health

Sleep is hugely under-rated as a cognitive enhancer – proper sleep is a necessity Main health effects of sleep deprivation (See Wikipedia:Sleep deprivation). Model: Mikael Häggström. To discuss image, please see Template talk:Häggström diagrams (Photo credit: Wikipedia) for learning and memory, processes at the core of cognition. But sleep has lots more functions than enhancing cognition.… Read More

Sharpen your thinking about business advice: Sensitivity, specificity and base rates

Your news feed might have pieces about how to get better at business (or indeed your living your life). They might have a seemingly empirical basis, and offer numbers of great specificity: the ten ways the successful manage their time; the fifteen books the very rich have read (and you must read too); the six… Read More

The Economic Impact of Irish Higher Education Institutions – Preliminary results

Originally posted on Brian M. Lucey:
So, what do higher education institutions add to the economy? A lot? a little? How would we know anyhow? A recent working paper suggests some answers. Today at the Dublin Economics Workshop Policy Conference we present this work. Its part of a larger project called TIONCHAR, that being the irish…

Acute phase plasma proteins are altered by electroconvulsive stimulation.

Acute phase plasma proteins are altered by electroconvulsive stimulation. J Psychopharmacol. 2014 Sep 29. pii: 0269881114552742. [Epub ahead of print] Glaviano A, O’Donovan SM, Ryan K, O’Mara S, Dunn MJ, McLoughlin DM. Download the paper. Abstract Electroconvulsive therapy (ECT) is an effective antidepressant treatment, but its molecular mechanisms of action remain to be fully elucidated.… Read More

First-in-class thyrotropin-releasing hormone (TRH)-based compound binds to a pharmacologically distinct TRH receptor subtype in human brain and is effective in neurodegenerative models

First-in-class thyrotropin-releasing hormone (TRH)-based compound binds to a pharmacologically distinct TRH receptor subtype in human brain and is effective in neurodegenerative models Highlights First-in-class TRH-based compound JAK4D detects new receptor subtype in human brain. JAK4D elicits statistically significant effects in neurodegenerative animal models. JAK4D crosses the blood–brain barrier and has a clean initial toxicology profile.… Read More

John O’Keefe being interviewed after his Nobel Prize win

John O’Keefe published his astounding paper (The hippocampus as a spatial map. Preliminary evidence from unit activity in the freely-moving rat) on the discovery of hippocampal place cells in 1971, using behavioural neurophysiological techniques that were difficult to establish and rare in nature. Place cells changed forever what we thought of the hippocampus and temporal lobe, and a vast… Read More

Nobel Prize 2014: Fortune favours the prepared mind

Originally posted on Speaking of Research:
Speaking of Research congratulates John O’Keefe, May-Britt Moser and Edvard I. Moser on being awarded the 2014 Nobel Prize in Physiology or Medicine “for their discoveries of cells that constitute a positioning system in the brain”. By recording the activity of individual nerve cells within the brains of rats…