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You might not like to admit it, but you’re related to me.

It’s very unlikely that you’re my sibling (I’m not even sure if my family read these posts). You’re one of over seven billion people alive today, and I have only one sister, so the chance that you as a random person are my sibling is < 1 in a billion. You’re not my first cousin, because (as far as I know) I dont have any first cousins. But further back than that it all starts it go a bit hazy. I have eight great-grandparents and I vaguely know their names and know some of their descendants, I’m guessing you’re not one of them (I met some of my 2nd cousins once at a Christmas long ago). But how far do I have to go back till I find I’m related to you? I have sixteen great-great grandparents, I…

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The whys and wherefores of the volitional control of breathing

Breathing above the brainstem: Volitional control and attentional modulation in humans.  Authors Jose Luis Herrero1, Simon Khuvis2, Erin Yeagle2, Moran Cerf3, and Ashesh D. Mehta4,* 1Feinstein Institute for Medical Research   2Laboratory of Human Brain Mapping,Feinstein Institute for Medical Research   3Northwestern University   4Hofstra North Shore LIJ School of Medicine and Feinstein Institute for… Read More

Brexit & “They need us more than we need them”

Originally posted on Nog's Musings:
The following is a fact and informed assumption based article.  It is not about patriotism, optimism, talking the country down or any other emotional aspects but simply a reasoned, logic based argument. Andrew Lilico has produced a report on “Seven key British perspectives on the Brexit negotiations“.  (See this…

Latest in Current Biology – Place Cells: Knowing Where You Are Depends on Knowing Where You’re Heading

Place Cells: Knowing Where You Are Depends on Knowing Where You’re Heading Shane M. O’Mara https://doi.org/10.1016/j.cub.2017.06.081 This piece is on this cracking paper by Harland ea. (abstract at bottom): Lesions of the Head Direction Cell System Increase Hippocampal Place Field Repetition Current Biology, Available online 31 August 2017 Summary Knowing where you are and knowing where… Read More

Our latest paper: Antidepressant-like effects of 3-carboxamido seco-nalmefene (3CS-nalmefene), a novel opioid receptor modulator, in a rat IFN-α-induced depression model

Antidepressant-like effects of 3-carboxamido seco-nalmefene (3CS-nalmefene), a novel opioid receptor modulator, in a rat IFN-α-induced depression model is published in Brain, Behaviour and Immunity Charlotte K. Callaghan, Jennifer Rouine, Reginald L. Dean, Brian I Knapp, Jean M. Bidlack, Daniel R. Deaver & Shane M. O’Mara  https://doi.org/10.1016/j.bbi.2017.08.016 Highlights IFN-α treatment induced depressive-like and cognitive deficits in the rat. IFN-α increased IL-6, IL-1β… Read More

Our latest: Exercise prevents IFN-α-induced mood and cognitive dysfunction and increases BDNF expression in the rat

Exercise prevents IFN-α-induced mood and cognitive dysfunction and increases BDNF expression in the rat Charlotte K. Callaghan , Jennifer Rouine, Shane M. O’Mara Highlights Treadmill running prevented IFN-α-induced anxiety- and depressive-like behavior in the open field test and forced swim test. Treadmill running prevented IFN-α-induced impairment in spatial memory in the object exploration task compared. Treadmill… Read More

Our latest paper (OA): The claustrum – Considerations regarding its anatomy, functions and a programme for research

The claustrum: Considerations regarding its anatomy, functions and a programme for research [OPEN ACCESS – DOWNLOAD] Christopher M. Dillingham, Maciej M. Jankowski, Ruchi Chandra, Bethany E. Frost and Shane M. O’Mara Abstract The claustrum is a highly conserved but enigmatic structure, with connections to the entire cortical mantle, as well as to an extended and… Read More

Science Gallery Dublin: Before The Story So Far

Originally posted on Ian Brunswick – On Science and Culture:
The Story So Far is the title of Science Gallery Dublin’s continually-evolving video summary of its evolution to date (latest version viewable here). This essay covers the years before it all began, principally 2006 and 2007, and investigates why and how Science Gallery came to…