Chronic immobilization stress occludes in vivo cortical activation in an animal model of panic induced by carbon dioxide inhalation

It has been known since at least the 1920’s that inhaling high amounts of CO2 (20%) induces panic attacks in healthy individuals. There is a remarkable literature deriving from diving and respiratory physiology in submariners available treating this topic. The great father and son team [John Scott Haldane (the physiologist and polymath) and J. B. S. Haldane (the physiologist,… Read More

What use are PhD’s? What future do they have?

 A picture attached to a tweet I received from Where will a biology PhD take you? Probably not academia: <8% of new PhDs will get tenure. via @jameswilsdon — Mo Costandi (@mocost) April 15, 2014 @mocost (and others) is profoundly depressing. It plots the number of biology PhD students in the US (86,000) against the… Read More

CREB selectively controls learning-induced structural remodeling of neurons.

Learn Mem. 2012 Jul 18;19(8):330-6. doi: 10.1101/lm.025817.112. CREB selectively controls learning-induced structural remodeling of neurons. [download] Middei S, Spalloni A, Longone P, Pittenger C, O’Mara SM, Marie H, Ammassari-Teule M. Source CNR-National Research Council, Rome 00143, Italy. Abstract The modulation of synaptic strength associated with learning is post-synaptically regulated by changes in density and shape of dendritic spines. The transcription factor… Read More