The Connected Hippocampus, 1st Edition, Preface and Table of Contents: O’Mara & Tsanov (ISBN-13: 978-0444635495)

The Connected Hippocampus: Preface Available here (Elsevier) and here (Amazon). The hippocampus is an intriguing and anatomically remarkable structure: it is possessed of a remarkable curvilinear appearance in coronal section, and it is easy to spot in anatomical section with the naked eye in just about any mammalian species. A special and important function has been ascribed to it… Read More


TRAUMA SCIENCE GALLERY DUBLIN Science Gallery Dublin Open for submissions from 11th May 09:00 to 4th June 16:00 Season dates: 20th November to 21st February Click here to apply TRAUMA is an international, open-call exhibition and events programme at Science Gallery Dublin that will explore biological, psychological, societal, and cultural trauma. A sudden, violent, stressful and disturbing event,… Read More

Kindness – How do Children Become Kind?

[This is a non-technical piece I did for the Powering Kindness campaign on the development of kindness in children, and how it relates to changes in brain function]. It’s an age-old argument – are we born to be kind to others or do we learn to be kind to others? Across all societies, humans of all ages… Read More

#sfn14 – As time goes by: The gradual impact of chronic stress on rodent hippocampal structure and function

I won’t be there but go see our poster anyway – presented by Mostafizur Rahmen. Program#/Poster#: 745.05/SS30 Presentation Title: As time goes by: The gradual impact of chronic stress on rodent hippocampal structure and function Location: WCC Hall A-C Presentation time: Wednesday, Nov 19, 2014, 8:00 AM -12:00 PM Presenter at Poster: Wed, Nov. 19,… Read More

Validation of the face-name pairs task in major depression: impaired recall but not recognition

Take-home Message: memory – and especially associative memory – is impaired in a wide variety of neuropsychiatric and neurological conditions. Face-name pair learning is a useful method to tap into deficits in associative memory; usefully, it is a task dramatically impaired by lesions of the extended hippocampal formation. Here, we show that patients with depression showed… Read More

Hippocampal Volume is Decreased in Adult-Onset Hypothyroidism.

Take-home message: We provide preliminary evidence that hypothyroidism results in structural deficits in the adult human brain. Decreases in volume in the right hippocampus were evident in patients with adult-onset overt hypothyroidism, supporting some of the findings in animal models. [Download the paper] Thyroid. 2013 Nov 8. Hippocampal Volume is Decreased in Adult-Onset Hypothyroidism. Cooke G, Mullally S, Correia N, O’Mara… Read More

Dissociation of dorsal hippocampal regional activation under the influence of stress [Front Behav Neurosci. 2011] – PubMed – NCBI

(Available for download as OA on Frontiers – just click through the link) via Dissociation of dorsal hippocampal regi… [Front Behav Neurosci. 2011] – PubMed – NCBI. Passecker J, Hok V, Della-Chiesa A, Chah E, O’Mara SM. Source Trinity College Institute of Neuroscience, Trinity College Dublin Dublin, Republic of Ireland. Abstract Stress has deleterious effects on brain, body, and behavior… Read More

Terrorism, Torture and Memory: Royal Irish Academy | About | Science Series

[My book ‘Why Torture Doesn’t Work: The Neuroscience of Interrogation’ (Harvard UP) can be preordered from Amazon (.com) – more details at end of post] Royal Irish Academy | About | Science Series via Royal Irish Academy | About | Science Series. This links to a podcast of an unusual interdisciplinary evening, featuring a neuroscientist (me), a political scientist (Richard… Read More

Suppressing the encoding of new information in memory: a behavioral study derived from principles of hippocampal function.

Take-home message: We show here that mixing tasks that involve executive control (the n-back task, requiring continual updating and discarding of information held presently ‘in mind’) inhibits dramatically performance on an explicit memory task (associative memory: face-name pair learning), but not performance on control recognition memory tasks. We therefore provide further behavioural evidence that memory subsystems… Read More