Decoding signal processing in thalamo-hippocampal circuitry: implications for theories of memory and spatial processing

Decoding signal processing in thalamo-hippocampal circuitry: implications for theories of memory and spatial processing Marian Tsanov and Shane M. O’Mara Our latest paper. Highlights • Thalamo-hippocampal projections are vital for episodic memory formation. • There is extensive connectivity between these structures. • We examine the signals processed within this circuitry. • We focus on head… Read More

Selective disconnection of the hippocampal formation projections to the mammillary bodies produces only mild deficits on spatial memory tasks: implications for fornix function.

Selective disconnection of the hippocampal formation projections to the mammillary bodies produces only mild deficits on spatial memory tasks: implications for fornix function. Take-home message: the mammillary bodies can  support spatial memory without their dense subicular complex inputs, revealing the importance of the other afferents for sustaining mammillary body function. This new evidence for independent functions… Read More

Why do I forget jobs I have completed? Bluma Zeigarnik, the Zeigarnik Effect and Memories from the Great Terror

‘What did you do at work today?’ ‘Lots – very busy indeed – lots happening…’ ‘But what did you do?’ ‘Err… hold on – I need to check my diary, emails and to do list…. but I was very busy’ [voice trails away, while wondering if there is some strange incipient amnesia on the way] Why… Read More

Exploring the recollective experience during autobiographical memory retrieval in amnestic mild cognitive impairment.

Take-home message: there are greater levels of autobiographical memory (memory for the episodes and events of your life and general knowledge of the world) impairment in amnestic mild cognitive impairment (aMCI: a greater than expected deficit in cognitive function for age and education) seen than previously assumed. More on MCI, which is often thought of as being prodromal for Alzheimer’s disease (AD), as a proportion of… Read More