Chronic immobilization stress occludes in vivo cortical activation in an animal model of panic induced by carbon dioxide inhalation

It has been known since at least the 1920’s that inhaling high amounts of CO2 (20%) induces panic attacks in healthy individuals. There is a remarkable literature deriving from diving and respiratory physiology in submariners available treating this topic. The great father and son team [John Scott Haldane (the physiologist and polymath) and J. B. S. Haldane (the physiologist,… Read More

Suppressing the encoding of new information in memory: a behavioral study derived from principles of hippocampal function.

Take-home message: We show here that mixing tasks that involve executive control (the n-back task, requiring continual updating and discarding of information held presently ‘in mind’) inhibits dramatically performance on an explicit memory task (associative memory: face-name pair learning), but not performance on control recognition memory tasks. We therefore provide further behavioural evidence that memory subsystems… Read More