Fornical and non-fornical projections from the rat hippocampal formation to the anterior thalamic nuclei.

Our latest paper available for download. We find that contrary to previous descriptions, projections from the subiculum to the anteromedial thalamic nucleus overwhelmingly relied on the fornix, whereas postsubicular inputs to the lateral dorsal part of the anteroventral nucleus, as well as to the anterodorsal and laterodorsal thalamic nuclei, largely proceed via the internal capsule (a non-fornical… Read More

Decoding signal processing in thalamo-hippocampal circuitry: implications for theories of memory and spatial processing

Decoding signal processing in thalamo-hippocampal circuitry: implications for theories of memory and spatial processing Marian Tsanov and Shane M. O’Mara Our latest paper. Highlights • Thalamo-hippocampal projections are vital for episodic memory formation. • There is extensive connectivity between these structures. • We examine the signals processed within this circuitry. • We focus on head… Read More

Acute phase plasma proteins are altered by electroconvulsive stimulation.

Acute phase plasma proteins are altered by electroconvulsive stimulation. J Psychopharmacol. 2014 Sep 29. pii: 0269881114552742. [Epub ahead of print] Glaviano A, O’Donovan SM, Ryan K, O’Mara S, Dunn MJ, McLoughlin DM. Download the paper. Abstract Electroconvulsive therapy (ECT) is an effective antidepressant treatment, but its molecular mechanisms of action remain to be fully elucidated.… Read More

Remind me again why aerobic exercise is good for my brain (and mood, and thinking)…

There are lots of reasons why regular aerobic exercise is good for the brain – the effects of exercise on brain volume, cognition and mood are profound and enduring. Here are a few key papers. In an early review paper, Colcombe and Kramer (2003) conducted a meta-analysis of 18 interventional studies, conducted over a 25-year period. Their… Read More

Suppressing the encoding of new information in memory: a behavioral study derived from principles of hippocampal function.

Take-home message: We show here that mixing tasks that involve executive control (the n-back task, requiring continual updating and discarding of information held presently ‘in mind’) inhibits dramatically performance on an explicit memory task (associative memory: face-name pair learning), but not performance on control recognition memory tasks. We therefore provide further behavioural evidence that memory subsystems… Read More