Long-term cognitive dysfunction in the rat following docetaxel treatment is ameliorated by the phosphodiesterase-4 inhibitor, rolipram.

Long-term cognitive dysfunction in the rat following docetaxel treatment is ameliorated by the phosphodiesterase-4 inhibitor, rolipram. Our latest paper [download] focuses on chemobrain – the mental fog or fuzziness that can accompany and follow chemotherapy. Behav Brain Res. 2015 May 1;290:84-89. doi: 10.1016/j.bbr.2015.04.044. [Epub ahead of print] Callaghan CK, O’Mara SM. Clinical studies report evidence of long-term… Read More

Blurb for my new book with HUP – Why Torture Doesn’t Work: The Neuroscience of Interrogation

‘Why Torture Doesn’t Work: The Neuroscience of Interrogation’ can now be preordered from: Amazon (.com) Amazon (.co.uk) Harvard University Press Torture is banned because it is cruel and inhumane. But as Shane O’Mara writes in this account of the human brain under stress, torture should never be condoned because it does not work the way torturers assume it… Read More

Physical Activity and the Prevention of Depression: A Systematic Review of Prospective Studies

Important systematic review evidence for the efficacy of physical activity on mood, adding further to the evidence base that exercise plays a very positive neuroregulatory role (see also this Cochrane systematic review downloadable here; and some of our own work here). Am J Prev Med. 2013 Nov;45(5):649-57. doi: 10.1016/j.amepre.2013.08.001. Physical activity and the prevention of depression: a systematic… Read More

Interactions Between Paired-Pulse Facilitation, Low-Frequency Stimulation And Behavioral Stress In The Pathway From Hippocampal Area CA1 To The Subiculum: Dissociation Of Baseline Synaptic Transmission From Paired-Pulse Facilitation And Depression Of The Same Pathway.

Here’s an old and difficult to access paper (Download: Commins & O’Mara Psychobiol) of ours from Psychobiology – from the days before all journals were online. Hard to remember those days now… Psychobiology evolved into Cognitive, Affective, & Behavioral Neuroscience (see past titles here – scroll to bottom). (This is the longest title on any paper I have ever published…) Commins,… Read More