Remind me again why aerobic exercise is good for my brain (and mood, and thinking)…

There are lots of reasons why regular aerobic exercise is good for the brain – the effects of exercise on brain volume, cognition and mood are profound and enduring. Here are a few key papers. In an early review paper, Colcombe and Kramer (2003) conducted a meta-analysis of 18 interventional studies, conducted over a 25-year period. Their… Read More

Exercise, but not environmental enrichment, improves learning after kainic acid-induced hippocampal neurodegeneration in association with an increase in brain-derived neurotrophic factor.

Take-home message: further evidence that aerobic exercise provides substantial neuroprotection against brain insult, even if there are equivalent losses of neurons in key brain regions compared to sedentary controls. [Download the paper] Much more on exercise. Exercise, but not environmental enrichment, improves learning after kainic acid-induced hippocampal neurodegeneration in association with an increase in brain-derived neurotrophic… Read More

Rosiglitazone enhances learning, place cell activity, and synaptic plasticity in middle-aged rats.

Rosiglitazone enhances learning, place cell activity, and synaptic plasticity in middle-aged rats. Wang BW, Hok V, Della-Chiesa A, Callaghan C, Barlow S, Tsanov M, Bechara R, Irving E, Virley DJ, Upton N, O’Mara SM. [Download here] Neurobiol Aging. 2012 Apr;33(4):835.e13-30. doi: 10.1016/j.neurobiolaging.2011.08.013. Epub 2011 Oct 4. Trinity College Institute of Neuroscience, Trinity College, Dublin, Ireland. Abstract As an antidiabetic agent, rosiglitazone (ROSI) binds and activates peroxisome proliferator-activator… Read More