Neuroanatomical investigations of the projections of the Papez circuit, with an emphasis on connections to the diencephalon

The projections of the extended hippocampal formation are still to a surprising extent under-described and under-investigated, despite the Papez circuit having been first postulated in 1937.  James Papez originally proposed that “the hypothalamus, the anterior thalamic nuclei, the gyrus cinguli, the hippocampus and their interconnections constitute a harmonious mechanism which may elaborate the functions of central emotion,… Read More