Mental simulation of the actions and intentions of others: What do rats know about what other rats might be thinking*? Speculations and potential experiments.

What do we know about the contents of the cognitions of other agents or conspecifics, either immediately present, or ones we have interacted with in the recent past in our environment? One important suggestion deriving from philosophy and cognitive science is that we and others engage in mental simulation. Mental simulation refers to the capacity to… Read More

Selective disconnection of the hippocampal formation projections to the mammillary bodies produces only mild deficits on spatial memory tasks: implications for fornix function.

Selective disconnection of the hippocampal formation projections to the mammillary bodies produces only mild deficits on spatial memory tasks: implications for fornix function. Take-home message: the mammillary bodies can  support spatial memory without their dense subicular complex inputs, revealing the importance of the other afferents for sustaining mammillary body function. This new evidence for independent functions… Read More

Deep layer prefrontal cortex unit discharge in a cue-controlled open-field environment in the freely-moving rat.

Take-home message: Prefrontal unit discharge principally reflects ongoing behavioural activity – what the rat was attending to or doing, rather than spatial position. Thus, prefrontal units show mixed responsivity, rather than a simple and single correlate. [Download the paper] Deep layer prefrontal cortex unit discharge in a cue-controlled open-field environment in the freely-moving rat. Behav Brain… Read More

Hippocampal dynamics predict interindividual cognitive differences in rats.

Hippocampal dynamics predict interindividual cognitive differences in rats. Take-home message: Individual memory in old rats was assessed using DNMS. We recorded hippocampal CA1 place cells as these rats explored a familiar environment; 27% of recorded pyramidal neurons showed substantial delayed onsets of place field activity. This age-related firing onset delay occurred under basal conditions; it was… Read More