Prolonged rote learning produces delayed memory facilitation and metabolic changes in the hippocampus of the ageing human brain.

Take-home message: repeated practice with material that must be remembered facilitates remembering in an aged population in whom there is expected to be a degree of age-related memory loss. This practice produces changes in the brain in structures that support learning and memory. Think of it like this: memory can be exercised via practice, much… Read More

Aerobic exercise improves hippocampal function and increases BDNF in the serum of young adult males.

Take-home message: It is becoming increasingly accepted that substantial, sustained low-impact aerobic exercise has profound effects on neurocognitive function in the aged (see, for example, this very important paper from Art Kramer’s group). We here focus on a young and sedentary population, using tasks that tap into hippocampal function. We also measure circulating brain-derived neurotrophic factor (BDNF) as a proxy for brain BDNF. We… Read More